mRNA-1273 COVID-19T

Jose Mateus1, Jennifer M Dan1,2, Zeli Zhang1

  • 1Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|September 14, 2021
PubMed
概括

莫德纳mRNA-1273疫苗产生强大的CD4+T细胞,CD8+T细胞和抗体反应. 已存在的T细胞记忆可以增强疫苗免疫力和抗体产生对抗SARS-CoV-2.

相关概念视频

Immunological Memory01:23

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
10.6K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
6.2K
Vaccinations01:51

Vaccinations

Overview
46.6K
Cross-reactivity00:42

Cross-reactivity

Overview
31.8K
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
1.1K
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
76.1K