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A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
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对型肝炎病毒受体结合和进入的结构洞察

Ashish Kumar1, Reafa A Hossain1, Samantha A Yost2

  • 1Structural Virology Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

Nature
|September 16, 2021
PubMed
概括

肝炎C病毒 (HCV) 的进入涉及E2糖蛋白与CD81受体的结合. 低pH和CD81结合诱导E2的结构变化,促进病毒膜融合.

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