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Updated: Oct 19, 2025

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
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Published on: January 16, 2016

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通过量子力学/分子力学,分子动力学和结构生物学研究的组合来重新设计酶

Hong-Yan Lin1, Xi Chen2, Jin Dong1

  • 1Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, International Joint Research Center for Intelligent Biosensor Technology and Health, College of Chemistry, Central China Normal University, Wuhan 430079, P.R. China.

Journal of the American Chemical Society
|September 20, 2021
PubMed
概括

酶工程的创新使新的化学反应成为可能. 研究人员使用QM/MM和模拟来重新设计4-基酸二氧化酶 (HPPD),创造产生基酸盐 (HPA) 等替代产品的突变物.

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