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编者纠正:针对NS3-NS4B相互作用的泛血清型登革热病毒抑制剂

Suzanne J F Kaptein1, Olivia Goethals2, Dominik Kiemel3

  • 1Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.

Nature
|October 21, 2021
PubMed
概括

No abstract available in PubMed .

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Inhibitors of Viral Protein Synthesis01:30

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Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...
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