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Updated: Aug 25, 2026

Generating iPS Cells from MEFS through Forced Expression of Sox-2, Oct-4, c-Myc, and Klf4
13:02

Generating iPS Cells from MEFS through Forced Expression of Sox-2, Oct-4, c-Myc, and Klf4

Published on: April 7, 2008

将转基因纤维细胞植入小鼠体内:对基因疗法的影响

R F Selden, M J Skoskiewicz, K B Howie

    Science (New York, N.Y.)
    |May 8, 1987
    PubMed
    概括

    这项研究证明了转质植入,一种新的基因疗法方法. 用于产生人类生长激素 (hGH) 的培养细胞植入小鼠体内,成功分泌hGH,并显示出对遗传疾病的治疗潜力.

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    Transplantation of Induced Pluripotent Stem Cell-derived Mesoangioblast-like Myogenic Progenitors in Mouse Models of Muscle Regeneration10:03

    Transplantation of Induced Pluripotent Stem Cell-derived Mesoangioblast-like Myogenic Progenitors in Mouse Models of Muscle Regeneration

    Published on: January 20, 2014

    Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes09:16

    Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes

    Published on: June 3, 2018

    相关概念视频

    In-vitro Mutagenesis01:16

    In-vitro Mutagenesis

    To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.