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Updated: Oct 14, 2025

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling
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Published on: March 20, 2018

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基因毒性C8-Arylamino-2'-deoxyadenosines作为潜伏化剂诱导DNA跨链

Aaron L Rozelle1,2, Seongmin Lee1

  • 1Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, The University of Texas at Austin, Austin, Texas 78712, United States.

Journal of the American Chemical Society
|November 2, 2021
PubMed
概括

多环芳氨酸可以在氧化应激下通过氧化8-arylamino-2'-deoxyadenosine损伤引起DNA跨链 (ICL),从而揭示新的基因毒性机制.

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