Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Reaction Mechanisms03:06

Reaction Mechanisms

27.3K
Chemical reactions often occur in a stepwise fashion, involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs.
For instance, the decomposition of ozone appears to follow a mechanism with two steps:
27.3K
Support Reactions01:30

Support Reactions

1.0K
A coplanar force system refers to a set of forces that all lie in the same plane and are subject to different reactions between the point of contact and the supports. Understanding how different types of supports affect coplanar forces is crucial for designing safe and reliable structures that can withstand external loads.
The purpose of the supports is to prevent the translational motion of the system by applying an equal and opposite force and to prevent the system's rotation by applying...
1.0K
Radical Reactivity: Overview01:11

Radical Reactivity: Overview

2.2K
Radicals, the highly reactive species, gain stability by undergoing three different reactions. The first reaction involves a radical-radical coupling, in which a radical combines with another radical, forming a spin‐paired molecule. The second reaction is between a radical and a spin‐paired molecule, generating a new radical and a new spin‐paired molecule. The third reaction is radical decomposition in a unimolecular reaction, forming a new radical and a spin‐paired...
2.2K
Reaction Rate02:53

Reaction Rate

56.7K
The rate of reaction is the change in the amount of a reactant or product per unit time. Reaction rates are therefore determined by measuring the time dependence of some property that can be related to reactant or product amounts. Rates of reactions that consume or produce gaseous substances, for example, are conveniently determined by measuring changes in volume or pressure.
The mathematical representation of the change in the concentration of reactants and products, over time, is the rate...
56.7K
Reaction Quotient02:35

Reaction Quotient

50.3K
The status of a reversible reaction is conveniently assessed by evaluating its reaction quotient (Q). For a reversible reaction described by m A + n B ⇌ x C + y D, the reaction quotient is derived directly from the stoichiometry of the balanced equation as
50.3K
Enzyme-linked Receptors01:00

Enzyme-linked Receptors

80.7K
Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...
80.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

An Ultra-High Throughput Hydrogen-Deuterium Exchange Workflow Using Acoustic Ejection Mass Spectrometry for Studying Peptide Solution Structural Conformation.

Analytical chemistry·2026
Same author

Pathway-Aware Template-Based Retrosynthesis.

Journal of chemical information and modeling·2026
Same author

Quantifying the failure modes of current one-step retrosynthesis models.

Chemical science·2026
Same author

A machine learning-based workflow for transaminase selection.

Chemical science·2026
Same author

An overview of reaction outcome prediction with physics-based and data-driven methods.

Chemical Society reviews·2026
Same author

An AI system to help scientists write expert-level empirical software.

Nature·2026
Same journal

On-Cell Detection of Polysaccharide One-Bond <sup>1</sup>J<sub>CH</sub> Couplings by Proton-Detected Solid-State NMR.

Journal of the American Chemical Society·2026
Same journal

Correction to "Unraveling the Effects of Fe Incorporation on High-Performance Water-Splitting Photoanodes".

Journal of the American Chemical Society·2026
Same journal

Proximity-Driven Protein Ligation Beyond the Concentration Limit.

Journal of the American Chemical Society·2026
Same journal

GraPhAI: Neural Networks for Solving Centrosymmetric Crystal Structures.

Journal of the American Chemical Society·2026
Same journal

Probing Stage Transition Kinetics in Li-Graphite Intercalation Compounds by Time-Resolved In Situ Solid-State NMR via <sup>13</sup>C Labeling.

Journal of the American Chemical Society·2026
Same journal

Dynamic Covalent Programming at DNA Base-Pairing Interfaces.

Journal of the American Chemical Society·2026
查看所有相关文章

相关实验视频

Updated: Oct 14, 2025

Detecting, Visualizing and Quantitating the Generation of Reactive Oxygen Species in an Amoeba Model System
16:41

Detecting, Visualizing and Quantitating the Generation of Reactive Oxygen Species in an Amoeba Model System

Published on: November 5, 2013

16.3K

开放的反应数据库

Steven M Kearnes1, Michael R Maser2, Michael Wleklinski3

  • 1Relay Therapeutics, Cambridge, Massachusetts 02139, United States.

Journal of the American Chemical Society
|November 2, 2021
PubMed
概括
此摘要是机器生成的。

开放反应数据库 (ORD) 为化学反应数据提供了标准化结构,克服了机器学习应用的障碍. 这项开放的倡议旨在推进计算机辅助合成和反应预测.

更多相关视频

Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling
08:24

Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling

Published on: November 11, 2008

16.5K
A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

17.9K

相关实验视频

Last Updated: Oct 14, 2025

Detecting, Visualizing and Quantitating the Generation of Reactive Oxygen Species in an Amoeba Model System
16:41

Detecting, Visualizing and Quantitating the Generation of Reactive Oxygen Species in an Amoeba Model System

Published on: November 5, 2013

16.3K
Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling
08:24

Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling

Published on: November 11, 2008

16.5K
A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

17.9K

科学领域:

  • 化学学
  • 数据科学
  • 计算化学

背景情况:

  • 化学反应数据通常是无结构的,
  • 这种缺乏标准化阻碍了下游应用,特别是化学机器学习模型的训练.
  • 现有的数据格式对获取和利用有价值的化学反应信息构成重大障碍.

研究的目的:

  • 引入一个开放的反应数据库 (ORD),一个开放的模式和基础设施.
  • 标准化有机反应数据的存储和共享.
  • 通过可访问的数据来促进先进的计算化学应用.

主要方法:

  • 开发了一种开放式访问方案来结构有机反应数据.
  • 建立了化学反应的集中数据库.
  • 在GitHub上公开提供方案,数据,支持代码和用户界面.
  • 确保该方案支持各种实验技术,包括高吞吐量和流量化学.

主要成果:

  • 开放反应数据库 (ORD) 的方案和基础设施现在已公开.
  • 该ORD支持各种化学反应类型和实验设置.
  • 已经建立了一个结构化有机反应数据的集中存储库.
  • 公共可访问的代码和接口促进了数据的使用和贡献.

结论:

  • 一个一致的数据表示和共享基础设施对于推进预测化学至关重要.
  • 预计ORD将显著改善计算机辅助合成规划和反应预测.
  • 这一举措旨在通过开放的数据访问来提高计算化学任务的技术水平.