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Updated: Oct 13, 2025

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半素的靠近性标记

Sudeshna Sen1,2, Nadia Sultana1,3, Scott A Shaffer1,3

  • 1Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, Massachusetts 01605, United States.

Journal of the American Chemical Society
|November 11, 2021
PubMed
概括

这项研究引入了一种新的化学方法,通过使用独特的自杀基质来标记附近的囊蛋白相互作用. 这种技术为了解细胞信号通路提供了一个新的工具.

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Labeling DNA Probes03:31

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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