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Updated: Oct 13, 2025

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression
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通过HUSH介导的无内部移动元件的沉默来监测基因组

Marta Seczynska1, Stuart Bloor1, Sergio Martinez Cuesta2

  • 1Cambridge Institute for Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.

Nature
|November 18, 2021
PubMed
概括

人类沉默枢纽 (HUSH) 复合体通过准内无基因元素来识别和沉默入侵的DNA,如逆转录病毒. 这种机制可以保护基因组免受外来DNA的影响.

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