对的治疗:一篇综述
Dawn Z Eichenfield1,2, Jessica Sprague1,2, Lawrence F Eichenfield1,2,3
1Department of Dermatology, University of California San Diego School of Medicine, La Jolla.
JAMA
|November 23, 2021
概括
是一种常见的皮肤病, 有效的治疗范围从局部视网剂治疗轻度病例到全身疗法,如口服抗生素或严重治疗的异类药物.
科学领域:
- 皮肤病学
- 炎症性皮肤疾病
背景情况:
- 是一种常见的炎症性皮肤病,影响着皮.
- 它影响全球约9%的人口,特别是青少年和年轻人.
- 会导致痕,生活质量下降以及心理压力.
研究的目的:
- 审查的分类和治疗.
- 突出第一线和先进的治疗方案.
主要方法:
- 根据年龄,病变形态,分布和严重程度进行分类.
- 首线局部治疗包括视网膜剂,过氧化物和阿泽莱酸的审查.
- 对严重的全身疗法的评估:口服抗生素,激素药物和异丁.
主要成果:
- 当地 tretinoin 显示了 63% 的病变数量减少.
- 组合口服避孕药 (COC) 显示,炎症病变减少了62%.
- 口服抗生素可以减少58%的炎症病变.
结论:
- 局部药物是大多数病例的主要治疗方法.
- 包括口服抗生素,激素药物 (COC,螺旋乳) 和异类药物在内的全身治疗对于严重或耐药的是有效的.
- 治疗选择取决于的严重程度,形态和患者因素.
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