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Updated: Feb 27, 2026

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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是否T细胞受体参与T细胞的杀死?

A Lanzavecchia

    Nature
    |February 5, 1986
    PubMed
    概括

    细胞毒性T淋巴细胞 (CTL) 需要T细胞受体 (TCR) 占用初始触发,但不能用于随后的杀死. 一旦激活,CTLs可以消除任何绑定细胞,使触发与致命打击机制分离.

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