针对COVID-19的诊断:从疫情应对转向控制
Rosanna W Peeling1, David L Heymann2, Yik-Ying Teo3
1Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK; Medical Microbiology Department, University of Manitoba, Winnipeg, Manitoba, Canada.
Lancet (London, England)
|December 23, 2021
概括
诊断测试对于COVID-19的应对至关重要. 分子,抗原和抗体测试在流行病过渡期间在检测,公共卫生查和监测方面发挥着独特的作用.
科学领域:
- 公共卫生
- 传染病诊断
- 流行病学
背景情况:
- 诊断对于管理COVID-19流行病至关重要.
- 目前有三种主要的SARS-CoV-2检测方法,其作用在不断变化.
研究的目的:
- 概述分子,抗原和抗体测试在COVID-19应对中的作用.
- 讨论这些诊断在不同流行病阶段的有用性.
主要方法:
- 对高灵敏度和特异性的分子试验 (PCR) 的审查.
- 对抗原快速检测测试进行分析,以确定速度,成本效益和传播风险.
- 对抗体测试的评估是为了监视和公共秩序,而不是为了证明免疫.
主要成果:
- 分子测试证实了有症状的病例,并指导了公共卫生措施.
- 抗原检测有助于快速查,保护易受伤害的群体,并支持安全的重新开放.
- 抗体测试有助于了解人口免疫力和告知政策.
结论:
- 这三种诊断方法对于从COVID-19流行病应对到控制的转变至关重要.
- 每种测试类型都为临床诊断,公共卫生查和流行病学监测提供了独特的优势.
- 诊断的战略性使用是管理SARS-CoV-2持续影响的关键.
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