光驱动的超快速生物灵感分子电机:指导和加速视网膜的光异构化动力学
Elisabeth Gruber1, Adil M Kabylda2, Mogens Brøndsted Nielsen3
1Department of Physics and Astronomy, Aarhus University, DK-8000 Aarhus C, Denmark.
Journal of the American Chemical Society
|December 27, 2021
概括
研究人员设计了一种锁定视网膜Schiff基 (L-RSB),它经历了超快的光异构化. 这一突破使得单向分子旋转成为可能,
科学领域:
- 摄影化学
- 分子工程
- 光谱学
背景情况:
- 视网膜质子化希夫基在罗多普辛中表现出超快的光异构.
- 蛋白质环境微调染色体光化学
- 对这些过程进行合成控制是可取的.
研究的目的:
- 调查是否可以在合成视网膜染色体中实现类似的光化学控制.
- 探索一个锁定视网膜希夫基的动态 (L-RSB).
- 评估设计光驱分子电机的潜力.
主要方法:
- 时间分辨率作用吸收光谱.
- 高级电子结构理论计算.
- 锁定二甲基视网膜希夫基 (L-RSB) 的合成.
主要成果:
- 在转变配置 (L-RSB) 中锁定希夫基加速激发状态衰变到亚皮秒状态.
- 通过C9C10路径进行异体化,这是由于固体阻碍和预扭曲,减少了能量障碍.
- 使用两个600nm光子,L-RSB在两个步骤中展示了单向的360°旋转 (全向-9-cis和反向).
结论:
- 视网膜染色体的合成工程可以模仿自然素的超快光化学反应.
- 锁定视网膜Schiff基提供了一个平台设计高效的,光驱动的分子旋转电机.
- 这项工作为创造新型红光激活分子机器开辟了道路.
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