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Updated: Oct 6, 2025

Photo-Induced Cross-Linking of Unmodified Proteins PICUP Applied to Amyloidogenic Peptides
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基于素的光性保护策略促进了有效的蛋白质组装

Siyao Wang1, Qingqing Zhou1, Yunxue Li1

  • 1Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China.

Journal of the American Chemical Society
|January 17, 2022
PubMed
概括

一种基于素的新型光性保护组 (PPG) 能够使用原生化学结合 (NCL) 和脱硫的表达蛋白结合 (EPL) 进行有效的蛋白质组合. 这种方法简化了蛋白质合成,并且与激进脱硫策略兼容.

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