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Updated: Oct 6, 2025

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碳化合物受约束的核酸调节RNA的混合动力学

Tamilselvan Rajasekaran1, Graeme C Freestone2, Rodrigo Galindo-Murillo3

  • 1Department of Chemistry, Université de Montréal, Quebec H3C 3J7, Canada.

Journal of the American Chemical Society
|January 18, 2022
PubMed
概括

通过碳化合物桥梁调节的混合动力来限制寡核酸 (ON) 骨干的灵活性. 宏循环ON显示出更快的解离,降低稳定性,而锁定核酸 (LNA) ON则改善双重稳定性.

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