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Updated: Oct 5, 2025

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
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危急的COVID-19肺炎的人类遗传和免疫学决定因素

Qian Zhang1,2,3, Paul Bastard4,5,6,7,

  • 1St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA. qzhang02@rockefeller.edu.

Nature
|January 28, 2022
PubMed
概括

影响I型干扰素 (IFN) 的遗传和自身免疫因素至少解释了15%的严重COVID-19肺炎病例. 呼吸道I型IFN免疫力不足可能导致严重的疾病,受年龄和性别的影响.

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