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Updated: Oct 4, 2025

Porous Silicon Microparticles for Delivery of siRNA Therapeutics
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Porous Silicon Microparticles for Delivery of siRNA Therapeutics

Published on: January 15, 2015

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基于状siRNA的球状核酸

Matthew K Vasher1,2, Gokay Yamankurt2,3, Chad A Mirkin1,2,4

  • 1Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United States.

Journal of the American Chemical Society
|February 10, 2022
PubMed
概括

新的小干扰RNA-球状核酸 (siRNA-SNA) 构造克服了传递挑战. 这种新型设计提高了siRNA的稳定性,降低了毒性,并提高了治疗应用的基因敲除效率.

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