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血小板丰富的血注射与安慰剂治疗关节炎患者

Theo Charnay1, Alain Silvestre2, Jeremy Magalon1

  • 1Cell Therapy Laboratory, Hôpital de la Conception, Marseille, France.

JAMA
|February 22, 2022
PubMed
概括

No abstract available in PubMed .

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Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
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