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Updated: Oct 2, 2025

Cholesterol Efflux Assay
07:54

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Published on: March 6, 2012

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胰岛素通过抑制12α-氧化胆汁酸来预防高胆固醇血症

Ivana Semova1, Amy E Levenson1, Joanna Krawczyk1

  • 1Division of Endocrinology (I.S., A.E.L., J.K., M.E.G., A.V.L., J.M., S.S.A., D.-J.S., S.C., S.B.B.), Boston Children's Hospital, Harvard Medical School, MA.

Circulation
|February 23, 2022
PubMed
概括

一型糖尿病会破坏胆固醇的新陈代谢,增加胆固醇的吸收. 胰岛素通常通过抑制FoxO1来降低胆固醇的吸收. 与他类药物不同,埃泽提米布有效地逆转了这些变化.

关键词:
胆汁酸和盐胆固醇糖尿病类型 1叉头盒蛋白质O1胰岛素精准医学

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