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Updated: Oct 2, 2025

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低剂量甲素通过PEN2向溶酶体AMPK通路

Teng Ma1, Xiao Tian1, Baoding Zhang1

  • 1State Key Laboratory for Cellular Stress Biology, Innovation Centre for Cell Signalling Network, School of Life Sciences, Xiamen University, Fujian, China.

Nature
|February 24, 2022
PubMed
概括

这是一种常见的糖尿病药物,直接与PEN2结合,PEN2是溶酶体中的一种蛋白质. 这种相互作用激活AMP激活蛋白激酶 (AMPK),解释了甲胺的抗衰老和抗癌功效.

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