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Updated: Oct 1, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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沉默突变显示了RAS Q61癌症的治疗脆弱性

Yoshihisa Kobayashi1,2,3, Chhayheng Chhoeu4, Jiaqi Li5

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. yoshikob@ncc.go.jp.

Nature
|March 3, 2022
PubMed
概括

研究人员发现一种无声的KRAS突变 (G60G) 对于癌症中的功能性KRAS (Q61K) 瘤基因产生至关重要. 这一发现揭示了一种新的治疗策略,通过干扰拼接来准RAS(Q61) 癌症.

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