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Updated: Sep 30, 2025

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
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人体肠道细菌产生T H 17调节胆酸代谢物

Donggi Paik1, Lina Yao2, Yancong Zhang3,4

  • 1Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.

Nature
|March 17, 2022
PubMed
概括

肠道细菌产生胆汁酸,抑制T助手17 (TH17) 细胞的分化. 这些免疫调节胆汁酸的水平降低与炎症性肠道疾病有关,这表明它们在肠道炎症中起作用.

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