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Updated: Sep 27, 2025

Author Spotlight: Advanced Single-Molecule Techniques for Investigating Telomeric Protein-DNA Interactions
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Published on: August 30, 2024

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人类活性端粒酶与端粒保护蛋白TPP1的结构

Baocheng Liu1, Yao He1,2, Yaqiang Wang1

  • 1Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, USA.

Nature
|April 14, 2022
PubMed
概括

人类端粒酶 (TERT) 和端粒酶RNA (TER) 结构揭示了特林蛋白TPP1如何招募和激活端粒酶. 这些发现揭示了端粒酶功能和潜在的药物点.

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