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Updated: Sep 27, 2025

Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations
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Published on: April 21, 2023

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通过增强剂-促进剂相互作用对转录进行非线性控制

Jessica Zuin1, Gregory Roth1, Yinxiu Zhan1

  • 1Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.

Nature
|April 14, 2022
PubMed
概括

影响基因转录的增强剂活动与其与促进体接触的概率有关,而不仅仅是接近. 这种非线性关系由促进体爆发动力学解释,澄清了增强剂如何在长距离工作以及染色体结构如何调节基因表达.

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