Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Mechanically-gated Ion Channels01:12

Mechanically-gated Ion Channels

6.8K
Mechanically-gated ion channels are proteins found in eukaryotic and prokaryotic cell membranes that open in response to mechanical stress. Tension, compression, swelling, and shear stress can alter the conformation of the protein, opening a transmembrane channel that allows the passage of ions for signal transmission. In eukaryotes, mechanically-gated channels are distributed in several regions like the neurons, lungs, skin, bladder, and heart, where they play critical roles in numerous...
6.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Flexible Crosslinked Poly(ionic liquid)s for All-Solid-State High-Performance Self-Powered Ionic Pressure Sensors.

ACS sensors·2026
Same author

Integrated Workflow for Electromechanical Stimulation of Cells in Active Scaffolds: From Live Cell Imaging to Functional Assays.

ACS biomaterials science & engineering·2026
Same author

Boosting mechanical-to-ionic transduction for self-powered piezoionic sensing.

Materials horizons·2025
Same author

Signal and Time Resolved Information Experiment (SATIRE): An NMR Supersequence for Monitoring Complex Environmental and Biological Processes without <sup>13</sup>C Enrichment.

Analytical chemistry·2025
Same author

Electro-switchable cellulose nanocrystal films with chiroptical properties.

Materials horizons·2025
Same author

Combining <sup>31</sup>P-<sup>1</sup>H Cross Polarization With Magnetization Transfer: A Novel Approach for Myelin Investigation.

NMR in biomedicine·2025

相关实验视频

Updated: Sep 25, 2025

One-channel Cell-attached Patch-clamp Recording
13:07

One-channel Cell-attached Patch-clamp Recording

Published on: June 9, 2014

24.6K

压离子机械受体:在水凝中强力诱导电流生成

Yuta Dobashi1,2,3, Dickson Yao1, Yael Petel4

  • 1Advanced Materials and Process Engineering Laboratory, University of British Columbia, Vancouver, BC, Canada.

Science (New York, N.Y.)
|April 28, 2022
PubMed
概括

研究人员使用将压力转化为离子电流的水凝开发了一种新的压离子皮肤. 这项技术模仿人类的体感系统,

更多相关视频

Preparation of Hydroxy-PAAm Hydrogels for Decoupling the Effects of Mechanotransduction Cues
11:31

Preparation of Hydroxy-PAAm Hydrogels for Decoupling the Effects of Mechanotransduction Cues

Published on: August 28, 2014

13.5K
Revealing Electromechanical Control of Tissue Homeostasis Using a Two-Layer Microfluidic Device
11:08

Revealing Electromechanical Control of Tissue Homeostasis Using a Two-Layer Microfluidic Device

Published on: September 19, 2025

12

相关实验视频

Last Updated: Sep 25, 2025

One-channel Cell-attached Patch-clamp Recording
13:07

One-channel Cell-attached Patch-clamp Recording

Published on: June 9, 2014

24.6K
Preparation of Hydroxy-PAAm Hydrogels for Decoupling the Effects of Mechanotransduction Cues
11:31

Preparation of Hydroxy-PAAm Hydrogels for Decoupling the Effects of Mechanotransduction Cues

Published on: August 28, 2014

13.5K
Revealing Electromechanical Control of Tissue Homeostasis Using a Two-Layer Microfluidic Device
11:08

Revealing Electromechanical Control of Tissue Homeostasis Using a Two-Layer Microfluidic Device

Published on: September 19, 2025

12

科学领域:

  • 材料科学
  • 生物物理
  • 神经科学

背景情况:

  • 人体体感官系统通过离子电流处理触觉信息.
  • 目前的人工感觉接口往往缺乏生物系统的灵敏度和适应性.

研究的目的:

  • 研究能够将压力转化为离子电流的水凝,从而形成"离子皮肤".
  • 探索这种皮质皮肤对神经调节和生物感官接口的潜力.

主要方法:

  • 具有不同阴离子和阴离子移动性的水凝膜的制造.
  • 有固定电荷梯度的水凝膜.
  • 压离子电流生成的特征及其对材料性能的依赖.

主要成果:

  • 在水凝中产生离子电流,模仿生物机械受体,持续时间可变 (毫秒到几百秒).
  • 这些电流表现出直接神经调节和肌肉激发的能力.
  • 通过控制离子移动性和固定电荷梯度来调整信号的大小和持续时间.
  • 开发的水凝的电荷密度明显高于现有的 triboelectric 和 piezoelectric 装置.

结论:

  • 基于水凝的皮质皮肤为实现自动供电的超软机械感应器提供了有前途的途径.
  • 这项技术在先进的生物感官接口和神经刺激中具有潜在的应用.
  • 这些发现强调了离子移动性和电荷梯度在设计有效的压离子材料中的重要性.