包括祖先在内的狗基因组挑战了流行的品种刻板印象
Kathleen Morrill1,2,3, Jessica Hekman3, Xue Li1,2,3
1Bioinformatics and Integrative Biology, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.
概括
大多数狗的行为是遗传的, 但品种只能解释一小部分的变化. 品种的特征行为很可能源于现代品种形成之前的古老遗传适应.
科学领域:
- 狗的行为遗传学
- 动物基因组学
- 种群遗传学
背景情况:
- 现代犬种是孤立的子群体,它们的行为被认为是不同的.
- 之前对狗的行为遗传学的研究主要集中在这些现代品种上.
研究的目的:
- 调查狗的行为特征的遗传基础.
- 为了确定品种对行为的影响程度.
- 探索特定品种行为的进化起源.
主要方法:
- 调查了18385名狗主人,
- 基因组测定了2,155只纯种和混合种的狗.
- 进行全基因组关联分析以确定行为位置.
主要成果:
- 大多数行为特征表现出显著的遗传性 (h2>25%).
- 这种品种只占个体行为变化的9%.
- 确定了11个与行为相关的显著位置,
- 这种品种的倾向与祖先的功能不太一致,
结论:
- 现代品种行为在很大程度上是由品种形成之前的古老多基因适应形成的.
- 现代犬种主要以美学特征而非行为特征来区分.
- 品种刻板印象并没有得到个人行为遗传数据的强烈支持.
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