使用乙烯 Ester 的代同化,对巴斯蒂莫利德 B 的完全合成进行立体控制

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Updated: Sep 24, 2025

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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Published on: November 30, 2022

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Daniele Fiorito1, Selbi Keskin1, Joseph M Bateman1

  • 1School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, U.K.

Journal of the American Chemical Society
|May 2, 2022
PubMed
概括

研究人员开发了一种新方法来合成1,5-多聚醇,这是一种在抗疟疾化合物巴斯蒂莫利德B中发现的具有挑战性的结构. 这种新的方法可以实现精确的立体控制,促进复杂分子的总合成.

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