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Updated: Sep 23, 2025

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
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Published on: May 10, 2022

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胆酸载体和HBV受体NTCP的结构

Jinta Asami1, Kanako Terakado Kimura2, Yoko Fujita-Fujiharu3,4,5

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.

Nature
|May 17, 2022
PubMed
概括

乙型肝炎病毒 (HBV) 使用大包膜糖蛋白 (LHBs) 结合宿主细胞受体. 这项研究揭示了通过NTCP进入HBV的结构基础,为了解病毒与宿主相互作用提供了一个框架.

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