相关实验视频

Updated: Sep 22, 2025

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
08:31

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions

Published on: December 1, 2020

5.2K

通过固态核磁共振进行皮质映射和结合性评估为通过设计的质量模式开发生物制剂提供了途径

Domenico Rizzo1,2, Linda Cerofolini1,3, Stefano Giuntini1,2

  • 1Magnetic Resonance Center (CERM), University of Florence, Via L. Sacconi 6, 50019 Sesto Fiorentino, Italy.

Journal of the American Chemical Society
|May 26, 2022
PubMed
概括

多种生物药物提供了更高的治疗效果和安全性. 固态NMR成功地映射了与新型多种生物药物相互作用的编程细胞死亡配体1 (PD-L1) 的残留物.

更多相关视频

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes07:59

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

Published on: March 25, 2014

15.1K
Mass Spectrometric Approaches to Study Protein Structure and Interactions in Lyophilized Powders11:14

Mass Spectrometric Approaches to Study Protein Structure and Interactions in Lyophilized Powders

Published on: April 14, 2015

16.2K

相关概念视频

Protein-Drug Binding: Determination Methods01:22

Protein-Drug Binding: Determination Methods

Determining protein-drug binding can be achieved through indirect and direct methods, each providing valuable insights into the interaction between proteins and drugs.
Indirect methods involve isolating the bound drug from its free form in biological samples such as blood, serum, or plasma. These techniques aim to measure the percentage of drugs bound to proteins. Equilibrium dialysis is a commonly used method where the free drug concentration at equilibrium is measured by separating the bound...
325