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类型III-E CRISPR-Cas7-11效应器组合的结构和工程

Kazuki Kato1, Wenyuan Zhou2, Sae Okazaki1

  • 1Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.

Cell
|June 1, 2022
PubMed
概括

Cas7-11 CRISPR-Cas系统为细菌和哺乳动物细胞提供双重RNA向能力. 结构洞察力使得能够设计一个紧的Cas7-11变体,用于使用AAV载体的体内RNA倒置应用.

关键词:
关于CRISPR的研究情况7-11对RNA进行向化电磁场

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