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使用合成IL-9受体增强采用细胞疗法

Anusha Kalbasi1,2, Mikko Siurala3,4, Leon L Su5

  • 1Department of Radiation Oncology, David Geffen School of Medicine and Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA. anushakalbasi@mednet.ucla.edu.

Nature
|June 8, 2022
PubMed
概括

具有新型嵌合体受体 (o9R) 的工程T细胞对固体瘤具有增强的抗瘤活性. 这种方法可以改善T细胞的功能而不需要化学疗法,

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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