Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Lifestyle Factors and Health01:20

Lifestyle Factors and Health

136
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
136
Regulation of Food Intake01:30

Regulation of Food Intake

545
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
545
Dietary Connections01:23

Dietary Connections

56.7K
In biological systems, most metabolic pathways are interconnected. The cellular respiration processes that convert glucose to ATP—such as glycolysis, pyruvate oxidation, and the citric acid cycle—tie into those that break down other organic compounds. As a result, various foods—from apples to cheese to guacamole—end up as ATP. In addition to carbohydrates, food also contains proteins and lipids—such as cholesterol and fats. All of these organic compounds are used...
56.7K
Mitochondria01:37

Mitochondria

15.2K
Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
15.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Time-restricted eating in adults with type 2 diabetes mellitus on concomitant glucagon-like peptide-1 receptor agonists: case report.

Frontiers in clinical diabetes and healthcare·2026
Same author

Time Restricted Feeding Mitigates High-Fat-Diet Induced Sleep Disruption and Amplifies NREM Substates.

bioRxiv : the preprint server for biology·2026
Same author

Time-Restricted Eating Promotes Weight Loss and Favorable Changes in Adipose in Obesity: The TREAD Randomized Control Trial.

Obesity (Silver Spring, Md.)·2026
Same author

Retinal ganglion cells expressing melanopsin.

Handbook of clinical neurology·2026
Same author

The diversity and consistency of what and when people eat.

Nature metabolism·2026
Same author

Relative Effects of Time-Restricted Eating, Energy-Restricted Eating, and Unrestricted Eating on Eating Patterns and Dietary Intake: Results From a Randomized Controlled Trial.

Journal of the Academy of Nutrition and Dietetics·2026

相关实验视频

Updated: Sep 20, 2025

Manipulation of Rhythmic Food Intake in Mice Using a Custom-Made Feeding System
07:34

Manipulation of Rhythmic Food Intake in Mice Using a Custom-Made Feeding System

Published on: December 16, 2022

2.4K

调整饮食时间以延长寿命

Shaunak Deota1, Satchidananda Panda1

  • 1The Salk Institute for Biological Studies, La Jolla, CA, USA.

Science (New York, N.Y.)
|June 9, 2022
PubMed
概括

限制卡路里和禁食与生理节律同步, 促进老鼠的长寿和健康. 这是延长寿命和改善幸福感的关键.

科学领域:

  • 长寿研究
  • 代谢健康
  • 时间生物学

背景情况:

  • 像卡路里限制和禁食这样的饮食干预措施可以延长寿命.
  • 身体内部的24小时时钟会影响新陈代谢.
  • 饮食时间和昼夜调整之间的相互作用是衰老研究的一个新兴领域.

研究的目的:

  • 在小鼠模型中研究卡路里限制,禁食和昼夜节律同步对健康和寿命的综合影响.
  • 确定饮食摄入量与自然昼夜周期的调整是否增强了CR和禁食的益处.

主要方法:

  • 小鼠接受了不同的饮食方案,包括随意食,卡路里限制和间歇性禁食.
  • 实验小组要么与自然的光暗周期同步,要么受到昼夜干扰.
  • 在整个研究过程中,关键的健康和寿命标志物得到了监测.

主要成果:

  • 与对照组相比,受益于卡路里限制,禁食和同步昼夜节律的小鼠的寿命显著延长.
  • 同步的饮食干预改善了代谢参数,并减少了与年龄相关的衰退.
  • 循环节律的干扰消除了饮食干预的一些积极影响.

结论:

更多相关视频

A Do-it-yourself System for Scheduled Feeding of Laboratory Rodents in Their Home Cage
04:49

A Do-it-yourself System for Scheduled Feeding of Laboratory Rodents in Their Home Cage

Published on: June 6, 2025

352
Author Spotlight: In Vitro Investigations of Circadian Rhythms in Multicellular Systems
05:44

Author Spotlight: In Vitro Investigations of Circadian Rhythms in Multicellular Systems

Published on: February 16, 2024

1.2K

相关实验视频

Last Updated: Sep 20, 2025

Manipulation of Rhythmic Food Intake in Mice Using a Custom-Made Feeding System
07:34

Manipulation of Rhythmic Food Intake in Mice Using a Custom-Made Feeding System

Published on: December 16, 2022

2.4K
A Do-it-yourself System for Scheduled Feeding of Laboratory Rodents in Their Home Cage
04:49

A Do-it-yourself System for Scheduled Feeding of Laboratory Rodents in Their Home Cage

Published on: June 6, 2025

352
Author Spotlight: In Vitro Investigations of Circadian Rhythms in Multicellular Systems
05:44

Author Spotlight: In Vitro Investigations of Circadian Rhythms in Multicellular Systems

Published on: February 16, 2024

1.2K
  • 限制卡路里摄入和禁食与生理节律的协调是促进寿命和健康的有效策略.
  • 维持饮食与内在生物钟的协调对于最大限度地提高代谢干预的好处至关重要.
  • 这些发现凸显了饮食策略中的时机的重要性.