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Mohamed A Abdelhalim1, Ashish Patel1, Jayne Moquet2

  • 1Academic Department of Vascular Surgery, School of Cardiovascular and Metabolic Medicine and Sciences, King's College London, British Heart Foundation Centre of Research Excellence and Guy's and St. Thomas' National Health Service Foundation Trust Biomedical Research Centre, United Kingdom (M.A.A., A.P., P.S., A.S., B.M.).

Circulation
|June 13, 2022
PubMed
概括

No abstract available in PubMed .

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Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
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