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Updated: Sep 8, 2025

Detection of Copy Number Alterations Using Single Cell Sequencing
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Published on: February 17, 2017

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人类癌症拷贝数变化的签名

Christopher D Steele1, Ammal Abbasi2,3,4, S M Ashiqul Islam2,3,4

  • 1Research Department of Pathology, Cancer Institute, University College London, London, UK.

Nature
|June 15, 2022
PubMed
概括

研究人员开发了一种新的框架来分析9,873种癌症中的DNA复制数变化. 这一框架确定了21种不同的复制号签名,揭示了人体瘤中各种潜在的突变过程.

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