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Updated: Sep 6, 2025

iCLIP - Transcriptome-wide Mapping of Protein-RNA Interactions with Individual Nucleotide Resolution
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细胞中小分子RNA结合部位的转录组宽映射告知了异型特异性降解剂

Yuquan Tong1, Quentin M R Gibaut1, Warren Rouse2

  • 1Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States.

Journal of the American Chemical Society
|June 23, 2022
PubMed
概括

研究人员发现了一种新型小分子F1,该小分子与RNA结合,向素硫氧化酶1异型a (QSOX1-a) mRNA. 这一发现使得针对癌症治疗的RNA降解系统的开发成为可能.

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