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核磁共振实验提供了对SARS-CoV-2尖端蛋白受体结合域的洞察

Robert Creutznacher1, Thorben Maass1, Barbora Veselkova2

  • 1Center of Structural and Cell Biology in Medicine, Institute of Chemistry and Metabolomics, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany.

Journal of the American Chemical Society
|July 13, 2022
PubMed
概括

核磁共振 (NMR) 在 SARS-CoV-2 尖端蛋白上确定了肝素, fondaparinux 和 lifitegrast 的结合部位. 一个生命的生命

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Conjugated Proteins02:50

Conjugated Proteins

Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
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