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Updated: Sep 4, 2025

In vitro Reconstitution of the Active T. castaneum Telomerase
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Published on: July 14, 2011

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聚合酶α-酶结合的CST的结构

Yao He1,2, He Song1, Henry Chan1

  • 1Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, USA.

Nature
|July 13, 2022
PubMed
概括

这项研究揭示了将DNA聚合酶α-初酶 (PolαPrim) 和CTC1-STN1-TEN1 (CST) 引入端粒的结构基础. 这些发现揭示了染色体末端的DNA合成协调.

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