社会信号的视觉识别由一个tectothalamic神经电路
Johannes M Kappel1, Dominique Förster1, Katja Slangewal1,2
1Max Planck Institute for Biological Intelligence (formerly Max Planck Institute of Neurobiology), Planegg, Germany.
Nature
|July 13, 2022
概括
研究人员在斑马鱼中确定了一条特定的大脑通路,负责社会吸引力. 这条途径涉及光学截面和背部丘脑,处理其他鱼类的视觉线索,使其有吸引力,同时将其与排斥行为分开.
科学领域:
- 神经科学是一个神经科学.
- 伦理学 伦理学 伦理学
- 系统生物学 系统生物学
背景情况:
- 社会归属依赖于由同类信号触发的行为规则.
- 吸引力和排斥力背后的机制和神经回路在很大程度上是未知的.
研究的目的:
- 研究同类物种视觉识别的神经基础.
- 确定控制斑马鱼社会吸引力和排斥力的神经回路.
主要方法:
- 在发育中的斑马鱼中利用了无偏向的活动映射和体积两光子成像.
- 在电子显微镜下进行了背部 thalamus 神经元的重建.
- 进行了光学结膜和背部丘脑的废除实验.
主要成果:
- 在背部丘脑中发现了生物运动调节的神经元,它们对视觉刺激的局部加速作出反应.
- 确定了一个带有光学点和投射到下丘脑区域的输入的带有光学点的途径.
- 证明切除视膜或背部丘脑有选择性地损害了社会吸引力,而不是排斥力.
结论:
- 纹状体的通路对于视觉识别同类物种至关重要.
- 这一途径将吸引力与社会归属中的排斥的神经控制分离开来.
- 揭示了斑马鱼集体行为背后的一个特定的神经电路.
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