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Updated: Sep 4, 2025

High-Resolution Complexome Profiling by Cryoslicing BN-MS Analysis
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对SHOC2-MRAS-PP1C全酸酶复合物的结构功能分析

Jason J Kwon1,2,3, Behnoush Hajian4, Yuemin Bian4

  • 1Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Nature
|July 13, 2022
PubMed
概括

该SHOC2-MRAS-PP1C复合体调节细胞信号传递. 研究人员确定了它的结构,揭示了RAS病变如何增强它的活性,并为癌症治疗开发提供了洞察力.

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