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由ZAKα驱动的核毒应激反应激活了人类的NLRP1炎症体

Kim S Robinson1,2, Gee Ann Toh3, Pritisha Rozario3

  • 1Skin Research Institute of Singapore (SRIS), 308232 Singapore.

Science (New York, N.Y.)
|July 20, 2022
PubMed
概括

人类NLRP1是一种天生的免疫传感器,通过核毒应激反应 (RSR) 检测紫外线B (UVB) 和毒素. 这引发了细胞死亡的过程, 提供了皮肤免疫力和RSR机制的新见解.

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