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相关概念视频

Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
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Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

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Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
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Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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Genomic DNA in Prokaryotes00:46

Genomic DNA in Prokaryotes

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The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
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Although bacterial genomes are much...
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DNA as a Genetic Template02:05

DNA as a Genetic Template

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相关实验视频

Updated: Sep 3, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
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建立基于区块链的基因组数据主权框架

Tim K Mackey1, Alec J Calac2, B S Chenna Keshava3

  • 1Global Health Program, Department of Anthropology, University of California, San Diego, San Diego, CA, USA; S-3 Research LLC, San Diego, CA, USA; Global Health Policy and Data Institute, San Diego, CA, USA; BlockLAB, San Diego Supercomputer Center, San Diego, CA, USA.

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概括

新的区块链框架将土著数据主权作为伦理健康基因组学的优先事项. 这种方法确保边缘化社区控制其宝贵的基因组数据, 解决技术差距.

关键词:
区块链分布式账本技术基因组学医疗公平原住民的健康

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科学领域:

  • 基因组学
  • 数据科学
  • 原住民研究

背景情况:

  • 在健康和基因组数据生成方面取得了快速进展.
  • 现有技术往往忽视了边缘化社区的价值观和优先事项.
  • 需要与社区需求一致的数据框架.

研究的目的:

  • 构想一个区块链基因组数据框架.
  • 将土著数据主权原则纳入基因组数据管理.
  • 提出一种以社区为中心的健康数据方法.

主要方法:

  • 概念框架的发展.
  • 关于区块链技术和土著数据主权的文献审查.
  • 对基因组数据实践当前缺陷的分析.

主要成果:

  • 提出了一个区块链基因组数据框架.
  • 这一框架建立在土著数据主权的原则之上.
  • 增强数据安全,控制和道德治理的潜力.

结论:

  • 区块链技术为基因组学中的土著数据主权提供了可行的解决方案.
  • 这种框架可以赋予边缘化社区管理其健康数据的权力.
  • 未来的工作应该集中在开发和测试这个框架在现实世界的应用.