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基因生成受损与COVID-19中的T细胞功能障碍有关

Fotios Karagiannis1, Konrad Peukert2, Laura Surace1,2

  • 1Immunopathology Unit, Institute of Clinical Chemistry and Clinical Pharmacology, Medical Faculty, University Hospital Bonn, University of Bonn, Bonn, Germany.

Nature
|July 28, 2022
PubMed
概括

基因生成产生β-基酸盐 (BHB),对于肺部感染中T细胞功能至关重要. 在严重的COVID-19中,BHB产量受损会阻碍免疫反应,但BHB补充可以恢复T细胞功能并降低死亡率.

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