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Updated: Jul 23, 2026

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工程发射纳米露西法酶及其用于免疫生物发光成像in vivo

Ying Xiong1,2, Yiyu Zhang1,2, Zefan Li1,2

  • 1Department of Molecular Physiology and Biological Physics, School of Medicine, University of Virginia, Charlottesville, Virginia 22908, United States.

Journal of the American Chemical Society
|August 1, 2022
PubMed
概括

研究人员开发了QLuc,一个红移生物发光记者,用于改善小鼠的深层组织成像. 这种新型系统可对瘤抗原进行非侵入性成像,补充了临床前研究中的现有技术.

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相关概念视频

Immunofluorescence Microscopy01:12

Immunofluorescence Microscopy

A fluorescence microscope uses fluorescent chromophores called fluorochromes, which can absorb energy from a light source and then emit this energy as visible light. Fluorochromes include naturally fluorescent substances (such as chlorophylls) and fluorescent stains that are added to the specimen to create contrast. Dyes such as Texas red and FITC are examples of fluorochromes. Other examples include the nucleic acid dyes 4’,6’-diamidino-2-phenylindole (DAPI), and acridine orange.
The...