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Updated: Sep 2, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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使用硫作为碳等效的孤儿环的有效合成

John Douglas Johnson1, Charles Reece Teeples1, Nicholas Rajai Akkawi1

  • 1Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, United States.

Journal of the American Chemical Society
|August 8, 2022
PubMed
概括

这项研究引入了一种使用硫离子合成1,1-二环的新方法. 这种方法克服了金属催化碳转移的局限性,使得有效的环生成成为可能.

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