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Updated: Aug 30, 2025

Direct Gene Knock-out of Axolotl Spinal Cord Neural Stem Cells via Electroporation of CAS9 Protein-gRNA Complexes
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Direct Gene Knock-out of Axolotl Spinal Cord Neural Stem Cells via Electroporation of CAS9 Protein-gRNA Complexes

Published on: July 9, 2019

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单细胞立体检测显示了参与轴突大脑再生的原始细胞

Xiaoyu Wei1,2, Sulei Fu3,4, Hanbo Li2,5,6

  • 1BGI-Hangzhou, Hangzhou 310012, China.

Science (New York, N.Y.)
|September 1, 2022
PubMed
概括

科学家使用空间转录学来探索头脑的再生. 他们发现脑内膜细胞可以成为神经元的原始体,

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Generation of Chimeric Axolotls with Mutant Haploid Limbs Through Embryonic Grafting07:17

Generation of Chimeric Axolotls with Mutant Haploid Limbs Through Embryonic Grafting

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Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo11:13

Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo

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相关概念视频

Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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