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Updated: Aug 30, 2025

Direct Gene Knock-out of Axolotl Spinal Cord Neural Stem Cells via Electroporation of CAS9 Protein-gRNA Complexes
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轴突脑组织,神经发生和再生的单细胞分析

Katharina Lust1, Ashley Maynard2, Tomás Gomes2

  • 1Research Institute of Molecular Pathology, Vienna Biocenter (VBC), Campus Vienna Biocenter, 1030 Vienna, Austria.

Science (New York, N.Y.)
|September 1, 2022
PubMed
概括

通过单细胞基因组学识别了沙兰的大脑细胞类型,发现与其他四足动物的相似之处. 这项研究探讨了大脑的组织和再生.

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Live Imaging Followed by Single Cell Tracking to Monitor Cell Biology and the Lineage Progression of Multiple Neural Populations10:55

Live Imaging Followed by Single Cell Tracking to Monitor Cell Biology and the Lineage Progression of Multiple Neural Populations

Published on: December 16, 2017

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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