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作为响应性纳米材料的细胞内刺激的宏分子拥挤

Daniel A Estabrook1, John O Chapman1, Shuo-Ting Yen2

  • 1Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.

Journal of the American Chemical Society
|September 9, 2022
PubMed
概括

研究人员开发出"拥挤反应"材料, 根据生物大分子度而不是温度而改变特性. 这种创新使得能响应刺激的材料能够在细胞环境中发挥作用.

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Cell-matrix's Response to Mechanical Forces01:13

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In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
Anchoring junctions mechanically attach a cell to the...