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Updated: Aug 28, 2025

Quantification of Atherosclerosis in Mice
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人类常见的APOE基因变异影响小鼠COVID-19死亡率

Benjamin N Ostendorf1,2,3,4, Mira A Patel5, Jana Bilanovic5

  • 1Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA. bostendorf@rockefeller.edu.

Nature
|September 21, 2022
PubMed
概括

阿波脂蛋白E (APOE) 基因变异影响COVID-19的严重程度. 在小鼠和人类中,APOE2和APOE4等位基因与更糟糕的结果,病毒载量增加和免疫反应受损有关.

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