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Updated: Aug 27, 2025

3D Multicolor DNA FISH Tool to Study Nuclear Architecture in Human Primary Cells
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3D Multicolor DNA FISH Tool to Study Nuclear Architecture in Human Primary Cells

Published on: January 25, 2020

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抑制和3D重组解决了进化重新排列基因组中的监管冲突

Alessa R Ringel1, Quentin Szabo2, Andrea M Chiariello3

  • 1Max Planck Institute for Molecular Genetics, Berlin, Germany; Institute for Medical and Human Genetics, Charité Universitätsmedizin Berlin, Berlin, Germany; Institute of Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany.

Cell
|September 30, 2022
PubMed
概括

新基因可以融入现有的调节区域,而不会破坏它们. 在特定的背景下,DNA甲基化防止干扰,允许独立的基因表达和进化灵活性.

关键词:
三维基因组组织在CTCFDNA 甲基化一致性发展基因调节增强剂-促进剂特异性一个进化面膜相关的领域循环挤出在拓上关联域

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