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Updated: Aug 26, 2025

Pancreatic Tissue Dissection to Isolate Viable Single Cells
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Published on: May 26, 2023

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取决于质溶解的DDR1信号决定了胰腺癌的结果

Hua Su1, Fei Yang2, Rao Fu2

  • 1Laboratory of Gene Regulation and Signal Transduction, Departments of Pharmacology and Pathology, School of Medicine, University of California San Diego, La Jolla, CA, USA.

Nature
|October 5, 2022
PubMed
概括

通过激活 DDR1 信号传递,基金属蛋白酶分裂的 I 型原蛋白 (cCol I) 促进胰腺癌的生长,而完整的 I 型原蛋白 (iCol I) 则抑制了这种生长. 这种途径影响患者的生存,并提供治疗点.

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